🐄 *Degnala Disease in Cattle* 🦠
*(Degnala Limb Disease/Syndrome)*
*Etiology (Causes)* 🦠
➖ *Primary Cause:*
▪ *Mycotoxins (Aflatoxins/Ochratoxins)* in *moldy feed* (sugarcane bagasse/rice straw).
▪ Fungi: Fusarium/Aspergillus/Penicillium spp.
➖ Risk Factors:
▪ Poor feed storage (humidity/heat).
▪ Nutritional deficiencies (Selenium/Vitamin E).
*Pathogenesis* ⚠
➡ Mycotoxin ingestion → *vascular damage* (vasculitis/thrombosis) → *ischemic necrosis* → *Gangrene in limbs/ears/tail*.
➡ *Clinical Signs*:
▪ Swelling/lameness
▪ Hoof/skin sloughing
▪ Fever, weight loss
*Treatment* 💊
➖ Immediate Care:
▪ 🚫 Replace moldy feed.
▪ 🩹 Clean wounds with povidone-iodine.
➖ Drugs & Dosage:
▪ *Sodium Thiosulfate (Detox)*: 25–50 mg/kg IV/IM (3–5 days).
▪ *Vitamin E + Selenium*: 1–2 mL/50 kg IM.
▪ *Flunixin (Pain):* 1.1–2.2 mg/kg IV/IM.
▪ *Oxytetracycline (Infection)*: 10–20 mg/kg IM/IV (5–7 days).
▪ *Ketoconazole (Fungal)*: 10–20 mg/kg oral.
*Prevention* 🛡
➖ Store feed in dry/ventilated areas.
➖ Add mycotoxin binders (bentonite/charcoal).
➖ Test feed regularly.
*https://chat.whatsapp.com/FN763N3jM9IFPxWu1SYYKR*
*(Degnala Limb Disease/Syndrome)*
*Etiology (Causes)* 🦠
➖ *Primary Cause:*
▪ *Mycotoxins (Aflatoxins/Ochratoxins)* in *moldy feed* (sugarcane bagasse/rice straw).
▪ Fungi: Fusarium/Aspergillus/Penicillium spp.
➖ Risk Factors:
▪ Poor feed storage (humidity/heat).
▪ Nutritional deficiencies (Selenium/Vitamin E).
*Pathogenesis* ⚠
➡ Mycotoxin ingestion → *vascular damage* (vasculitis/thrombosis) → *ischemic necrosis* → *Gangrene in limbs/ears/tail*.
➡ *Clinical Signs*:
▪ Swelling/lameness
▪ Hoof/skin sloughing
▪ Fever, weight loss
*Treatment* 💊
➖ Immediate Care:
▪ 🚫 Replace moldy feed.
▪ 🩹 Clean wounds with povidone-iodine.
➖ Drugs & Dosage:
▪ *Sodium Thiosulfate (Detox)*: 25–50 mg/kg IV/IM (3–5 days).
▪ *Vitamin E + Selenium*: 1–2 mL/50 kg IM.
▪ *Flunixin (Pain):* 1.1–2.2 mg/kg IV/IM.
▪ *Oxytetracycline (Infection)*: 10–20 mg/kg IM/IV (5–7 days).
▪ *Ketoconazole (Fungal)*: 10–20 mg/kg oral.
*Prevention* 🛡
➖ Store feed in dry/ventilated areas.
➖ Add mycotoxin binders (bentonite/charcoal).
➖ Test feed regularly.
*https://chat.whatsapp.com/FN763N3jM9IFPxWu1SYYKR*